area 46 (46)

The term area 46 refers to an area defined by internal structure and located centrally in the middle frontal gyrus. It is identified on the basis of multiple stains. A roughly circular area in the human, it is surrounded, except for its rostral tip, by area 9/46. It is equivalent to area 46 of Brodmann. Architectonically it is one of four parts of the dorsolateral prefrontal cortex. The others are area 8, area 9, and area 9/46 ( Petrides-2012 ). Its equivalent in the macaque is topologically similar, except that it is more oval in shape and is not embedded in area 9/46; it extends rostrally from area 9/46, ventral to area 9 and dorsal to area 12 ( Petrides-2012 ). As granular prefrontal cortex, it has no equivalent in the rat ( Zilles-2012 ).

Also known as: area 46, area 46 of cortex

NeuroNames ID: 3527

All Names & Sources

Showing 3 synonym(s)

Name:

area 46

Language:

English

Organism:

human

Citation:

Chapter 26 in The Human Nervous System, Third Edition, JK Mai and G Paxinos (Eds.), pp. 618-677, Amsterdam: Elsevier.

Source Title:

The Frontal Cortex

Name:

46

Language:

acronym

Organism:

human

Citation:

Chapter 26 in The Human Nervous System, Third Edition, JK Mai and G Paxinos (Eds.), pp. 618-677, Amsterdam: Elsevier.

Source Title:

The Frontal Cortex

Name:

area 46 of cortex

Language:

English

Organism:

macaque

Citation:

Chapter 2 in The Rhesus Monkey Brain, Second Edition. Amsterdam: Elsevier/Academic Press

Source Title:

A Delineation of the Monkey Cortex on the Basis of the Distribution of a Neurofilament Protein

Illustrations
No specie structures found

No specie structures available for this concept.

Models Where It Appears
Topographic Model of Human Cerebral Cortex

The topographic model of human cerebral cortex is a closed partitive hierarchical model of cerebral cortical structure in the human. The cerebral cortex is segmented on the basis of internal structure, connectivity, and/or functions of cortical areas. It is designed to update the comprehensive early twentieth century parcellations of Brodmann and of von Economo and Koskinas and their successors. A work in progress, it integrates the most authoritative, comprehensive, and recent parcellations and nomenclatures from peer-reviewed publications and neuroanatomical texts. For an equivalent model in the rodent, Search BrainInfo for ' Functional CNS Model - Rat '. This segmentation of the human cerebral cortex, based on a combination of internal structure, connectivity, and function, complements the classical segmentation of the cerebral cortex into lobes, lobules, and gyri based on sulcal patterns: For the classical segmentation, see ' cerebral cortex ' and click 'Locus in Brain Hierarchy'.