linear nucleus of the raphe

linear nucleus of the raphe (LIR)

The term linear nucleus of the raphe (LIR) refers to a narrow vertical group of cells located in the midline of the ventral midbrain tegmentum.Identified by internal structure, it is Found in the human ( Paxinos-2012 ), the macaque ( Paxinos-2009a ), the rat ( Swanson-2004 ) and the mouse ( Dong-2004 ), it consists of two components: the rostral linear nucleus of the raphe and the caudal linear nucleus of the raphe. Functionally it is part of the behavioral state system ( Swanson-2004 ). Cells in LIR contain dopamine and are part of the A10 cell group ( Felten-1983 ). Updated 25 Aug 2024.

Also known as: linear nucleus, Nucleus linearis, rostral and caudal linear nuclei of the raphe, linear nucleus of the raphe, nucleus linearis intermedius

NeuroNames ID: 519

All Names & Sources

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English

linear nucleus

Crosby-1962

English

linear nucleus of the raphe

NeuroNames

English

rostral and caudal linear nuclei of the raphe

Bowden-1997

Illustrations

Showing 3 illustration(s)

labeled line drawings of
sagittal section in
Macaca fascicularis

multiple views of
3D reconstruction in
Macaca mulatta

Nissl stain & diagram of
sagittal section in
mouse

Species With The Structure

Equivalent By	Human	Macaque	Rat	Mouse
Internal Structure	Has The Structure	Has The Structure	Has The Structure	Relevant Data Not Located

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Basis

Has Equivalent

Organism

Their Name

Source

Internal Structure

Yes

Homo sapiens (human)

linear nucleus

Crosby-1962

Internal Structure

Yes

Homo sapiens (human)

Nucleus linearis

Carpenter-1983

Internal Structure

Yes

Macaca mulatta (Macaca mulatta)

Nucleus linearis

Francois-1984

Internal Structure

Yes

Rattus (rat)

rostral and caudal linear nuclei of the raphe

Bowden-1997

Models Where It Appears

Structural CNS Model - Macaque

Brain structures of the macaque are illustrated in BrainInfo’s NeuroMaps macaque brain atlas. Structures are grouped by proximity in a hierarchy corresponding to the central nervous system hierarchy of NeuroNames ( Bowden-1995 Martin-2000 ). Structures in the NeuroMaps atlas are based on the segmentation of an MRI of the brain of a 3-year old male rhesus macaque (Macaca mulatta). The atlas is most useful for targeting structures for implantating electrodes and chemtrodes. Updated 29 Oct 2025.

cerebral crus (crus cerebri)

hindbrain

choroidal fissure