gray matter

The term gray matter refers to one of two structural components of the central nervous system (CNS). It is a type of neural tissue of the brain (BRN) and spinal cord (SPC) that, cut fresh appears pink or tan and fixed appears darker compared to the other type, white matter. In MRI images it can be darker gray or lighter gray than white matter depending on whether the image is T1 or T2 weighted and other factors.. Most gray matter is classified as an area of cortex or a nucleus. gray matter is composed predominantly of nerve and glial cell bodies ( Schiebler-1999 ). It is found in all parts of the CNS of the human, macaque, rat, mouse, and other vertebrates ( Swanson-2004, Swanson-2015 ). In NeuroNames, acronyms for gray matter structures or combinations of gray matter and white matter structures are three-letter combinations of capital letters followed by lower case letters representing substructures, spatial location and other features, e.g., AMGbl for basolateral nucleus of the amygdala. Final 30 Apr 2025.

Also known as: basic cell groups, basic cell groups and regions, central nervous system gray matter, grey matter, gray matter , Substantia grisea

NeuroNames ID: 2869

All Names & Sources

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Language
Name
Source
English
basic cell groups
English
basic cell groups and regions
English
central nervous system gray matter
English
gray matter
English
grey matter
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Species With The Structure
Equivalent By Human Macaque Rat Mouse
Internal Structure Has The Structure Relevant Data Not Located Has The Structure Has The Structure

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central nervous system gray matter
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basic cell groups
Internal Structure
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basic cell groups and regions
Models Where It Appears
Functional CNS Model - Rat

The Functional CNS Model - Rat (FMrat) ( Swanson-2004) is one of three hierarchical models representing the internal organization of the central nervous system (CNS). The others are the Structural CNS Model - Human (SThmn) and the Functional CNS Model - Human (FMhmn). The FMrat model represents the basic organization of the mouse ( Hof-2000 AMBA-2024 ) and, presumably, other rodents. Functional CNS models differ from structural models in that structures are defined and named by connectivity rather than by proximity to other structures at the same level. Functional models are more useful for representing longitudinal components of are grouped based on information drawn from multiple neuroscientific disciplines. such as connections, neurochemical characteristics, and role in physiogical and behavioral processes. While the Functional Model was developed primarily for an atlas of the rat brain ( Swanson-2004 ), the hierarchical organization of structures is for the most part applicable to the human, macaque, mouse and other mammalian brains as well. Structures at lower levels of the Functional CNS hierarchy are largely the same as in the Classical and Developmental Models, i.e., they were originally identified by stains for gray matter (Nissl substance) and white matter (myelin). At the next higher level they are grouped into basic connectional and functional systems of the CNS, such as the subcortical sensory systems, the brainstem motor system and the behavioral state system. At the highest levels CNS structures are grouped on the basis of dissection and embryologic precursors into cerebrum ( cerebral cortex and cerebral nuclei ), cerebellum, and cerebrospinal trunk.