white matter

The term white matter refers to one of two types of tissue found in the central nervous system (CNS) . It is neural tissue of the brain (BRN) and spinal cord (SPC) that, whether fresh or fixed, appears lighter compared to the other type, gray matter. White matter is composed predominantly of myelinated nerve axons, which give the cortical white matter (cow), tracts and fasciculi of the CNS their white color on dissection ( Schiebler-1999 ). In MRI images it can appear whiter or grayer than gray matter depending on whether the image is T1 or T2 weighted and other factors. NeuroNames acronyms for White matter structures are in lower case, e.g., crc for cerebral crus. White matter is found in the human, macaque, rat, mouse and other vetebrates ( Swanson-2015 ). Updated 30 Apr 2025.

Also known as: basic fiber systems, central nervous system white matter, white matter, Substantia alba, white matter tracts

NeuroNames ID: 2870

All Names & Sources

Showing 7 synonym(s)

Name:

basic fiber systems

Language:

English

Organism:

rat

Source:

Swanson-2004

Citation:

Third Edition, Elsevier Academic Press, Oxford, 2004

Source Title:

Brain Maps: Structure of the Rat Brain.

Name:

central nervous system white matter

Language:

English

Organism:

human

Source:

Lau-2009

Citation:

Inflamm Bowel Dis. 2009 Apr;15(4):576-80

Source Title:

Acute CNS White Matter Lesions in Patients with Inflammatory Bowel Disease

Name:

central nervous system white matter

Language:

English

Organism:

rat

Source:

Swanson-2004

Citation:

Third Edition, Elsevier Academic Press, Oxford, 2004

Source Title:

Brain Maps: Structure of the Rat Brain.

Name:

white matter

Language:

English

Organism:

Unspecified

Citation:

Source Title:

Lamina terminalis

Name:

Substantia alba

Language:

Latin

Organism:

human

Citation:

Eighth Edition, Springer Verlag, Berlin, 1999.

Source Title:

Anatomie

Name:

weisse Substanz

Language:

German

Organism:

human

Citation:

Eighth Edition, Springer Verlag, Berlin, 1999.

Source Title:

Anatomie

Name:

white matter tracts

Language:

English

Organism:

human

Source:

Swanson-2015

Citation:

Oxford: Oxford University Press, 2015.

Source Title:

Neuroanatomical Terminology: A Lexicon of Classical Origins and Historical Foundtions

No illustrations found

No illustrations available for this concept.

Species With The Structure
Equivalent By Human Macaque Rat Mouse
Internal Structure Has The Structure Relevant Data Not Located Has The Structure Has The Structure

Showing 3 record(s)

Basis:

Internal Structure

Has Equivalent:

Yes

Their Name:

central nervous system white matter

Source:

Lau-2009

Basis:

Internal Structure

Has Equivalent:

Yes

Organism:

Rattus (rat)

Their Name:

basic fiber systems

Source:

Swanson-2004

Basis:

Internal Structure

Has Equivalent:

Yes

Organism:

Mus (mouse)

Their Name:

---

Source:

NeuroNames

Models Where It Appears
Functional CNS Model - Rat

The Functional CNS Model - Rat (FMrat) ( Swanson-2004) is one of three hierarchical models representing the internal organization of the central nervous system (CNS). The others are the Structural CNS Model - Human (SThmn) and the Functional CNS Model - Human (FMhmn). The FMrat model represents the basic organization of the mouse ( Hof-2000 AMBA-2024 ) and, presumably, other rodents. Functional CNS models differ from structural models in that structures are defined and named by connectivity rather than by proximity to other structures at the same level. Functional models are more useful for representing longitudinal components of are grouped based on information drawn from multiple neuroscientific disciplines. such as connections, neurochemical characteristics, and role in physiogical and behavioral processes. While the Functional Model was developed primarily for an atlas of the rat brain ( Swanson-2004 ), the hierarchical organization of structures is for the most part applicable to the human, macaque, mouse and other mammalian brains as well. Structures at lower levels of the Functional CNS hierarchy are largely the same as in the Classical and Developmental Models, i.e., they were originally identified by stains for gray matter (Nissl substance) and white matter (myelin). At the next higher level they are grouped into basic connectional and functional systems of the CNS, such as the subcortical sensory systems, the brainstem motor system and the behavioral state system. At the highest levels CNS structures are grouped on the basis of dissection and embryologic precursors into cerebrum ( cerebral cortex and cerebral nuclei ), cerebellum, and cerebrospinal trunk.