orbitomedial prefrontal cortex (OMPFC)

The term orbitomedial prefrontal cortex (OMPFC) refers to a combination of some 20 histologically defined areas in rostral frontal lobe (FLB) and the anterior cingulate gyrus (ACG) of the limbic lobe (LLB). In the human OMPFC includes areas of the transverse frontopolar gyri (FPG), the orbital gyri (ORG), the frontomarginal gyrus (FMG), and the inferior rostral gyrus (RSGi) of the FLB, together with ventral parts of the ACG of the LLB ( Ongur-2003 ). For a listing of subdivisions, see orbitomedial prefrontal cortex hierarchy. In the macaque OMPFC, most of the same subdivisions are found except that area 10 in the human is divided into a medial area 10m, a rostral area 10r and a polar area 10p, in the macaque it is divided in to a larger histologically equivalent area 10m, and much smaller histologically distinct orbital area 10o. Also, the macaque equivalent to area 47/12 of the human is named simply area 12 and human area 32pl has no equivalent in the macaque ( Carmichael-1994 ). ‘Prefrontal’ in the name can be a source of confusion in comparing and contrasting primates and Rodents neuroanatomy. In primates (and humanocentric NeuroNames), ' prefrontal cortex' refers to granular and dysgranular cortex in the rostral-most areas of cerebral cortex (CTX). Rodents have no histologically equirvalent areas ( Preuss-2022 ), . Updated 27 Sep 2024.

Also known as: orbital and medial prefrontal cortex, orbitomedial prefrontal cortex

NeuroNames ID: 3506

All Names & Sources

Showing 3 synonym(s)

Name:

orbital and medial prefrontal cortex

Language:

English

Organism:

human

Source:

Ongur-2003

Citation:

J Comp Neurol. 2003 Jun 2;460(3):425-49.

Source Title:

Architectonic subdivision of the human orbital and medial prefrontal cortex

Name:

orbitomedial prefrontal cortex

Language:

English

Organism:

Unspecified

Source:

NeuroNames

Citation:

University of Washington, Seattle, WA

Source Title:

NeuroNames

Name:

OMPFC

Language:

acronym

Organism:

human

Source:

Ongur-2003

Citation:

J Comp Neurol. 2003 Jun 2;460(3):425-49.

Source Title:

Architectonic subdivision of the human orbital and medial prefrontal cortex

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Models Where It Appears
orbitomedial prefrontal cortex hierarchy

refers to the organization of substructures of the orbitomedial prefrontal cortex of the human as described in Ongur-2003. The organization is the same in the macaque, except for a few minor differences in internal structure and names based on topology ( Carmichael-1994 ).