lateral prefrontal cortex (LPFC)
The term lateral prefrontal cortex refers to one of two components of prefrontal cortex defined on the basis of internal structure in the human and the macaque. It is located on the outer and upper surfaces of the frontal lobe. In the human it occupies the lateral and rostral parts of the transverse frontopolar gyri, the superior frontal gyrus, the middle frontal gyrus, and the inferior frontal gyrus. It is topologically similar in the macaque, except that the macaque lacks transverse frontopolar gyri.
In both human and macaque it is composed of the dorsolateral prefrontal cortex and the ventrolateral prefrontal cortex. The other component of prefrontal cortex is the orbitomedial prefrontal cortex. Some authors distinguish a frontopolar area ( Petrides-2012 ),.
Early authors used the term 'dorsolateral' prefrontal cortex to refer to the entire lateral prefrontal cortex, as distinct from the orbitomedial prefrontal cortex ( Preuss-1995 ).
The rat, lacking significant granular cortex at the frontal pole does not have an equivalent cortical area ( Preuss-1995; Wallis-2012 ).
Also known as: lateral prefrontal cortex, dorsolateral prefrontal cortex
NeuroNames ID: 3508