substantia innominata (SI)

The term substantia innominata refers to a predominantly cellular portion of the basal endbrain defined on the basis of Nissl stain. caudal to the anterior commissure it lies deep to the globus pallidus and dorsal to the amygdala. rostral to the anterior commissure it lies deep to the striatum. The more rostral portion contains the basal nucleus ( Anthoney-1994 ). In the late twentieth century the region containing the substantia innominata was resegmented on the basis of neurochemistry and connectivity to constitute the striatopallidal system ( Heimer-1995 ). In this scheme the caudal portion of substantia innominata is located largely in the ventral pallidum and the rostral portion in the ventral striatum.

Also known as: substantia innominata (Reil, Reichert), substantia innominata, Substantia innominata, Substantia innominata of Reichert, Substantia innominata of Reil, Substantia innominata of Meynert, substriatal gray

NeuroNames ID: 274

All Names & Sources

Showing 13 synonym(s)

Name:

substantia innominata (Reil, Reichert)

Language:

English

Organism:

rat

Source:

Swanson-1998

Citation:

Second Revised Edition, Elsevier Science, Amsterdam, 1998

Source Title:

Brain Maps: Structure of the Rat Brain

Name:

sostanza innominata

Language:

Italian

Organism:

human

Citation:

EdiSes, s.r.l.- Napoli, 1995

Source Title:

Fondamenti di Neuroanatomia

Name:

SI

Language:

acronym

Organism:

mouse

Source:

Hof-2000

Citation:

Elsevier, Amsterdam, 2000

Source Title:

Comparative Cytoarchitectonic Atlas of the C57BL/6 and 129/Sv Mouse Brains

Name:

substantia innominata

Language:

English

Organism:

human

Citation:

Baltimore: Williams and Wilkins Co., 1983

Source Title:

Human Neuroanatomy

Name:

substantia innominata

Language:

English

Organism:

rat

Source:

Bowden-1997

Citation:

Source Title:

A digital Rosetta stone for primate brain terminology

Name:

Substantia innominata

Language:

Latin

Organism:

Macaca fascicularis

Source:

Shantha-1968

Citation:

Baltimore: Williams and Wilkins, 1968

Source Title:

A Stereotaxic Atlas Of The Java Monkey Brain (Macaca irus)

Name:

Substantia innominata of Reichert

Language:

Latin

Organism:

human

Source:

Crosby-1962

Citation:

New York: MacMillan, 1962

Source Title:

Correlative Anatomy of the Nervous System

Name:

Substantia innominata of Reil

Language:

Latin

Organism:

human

Citation:

Boca Raton, Florida: CRC Press, 1994

Source Title:

Neuroanatomy And The Neurologic Exam: A Thesaurus of Synonyms, Similar Sounding Non-Synonyms And Terms Of Variable Meaning

Name:

Substantia innominata of Meynert

Language:

Latin

Organism:

human

Citation:

Boca Raton, Florida: CRC Press, 1994

Source Title:

Neuroanatomy And The Neurologic Exam: A Thesaurus of Synonyms, Similar Sounding Non-Synonyms And Terms Of Variable Meaning

Name:

sustancia innominada

Language:

Spanish

Organism:

human

Citation:

edicion 4, Williams & Wilkins, Baltimore; traducción de Editorial Medica Panamericana, Buenos Aires, efectuada por el Dr. Alejandro Kaufman

Source Title:

Neuroanatomía Fundamentos

Name:

substance innominée

Language:

French

Organism:

human

Citation:

Springer-Verlag, Paris, 1992

Source Title:

Le cerveau humain: Surface, coupes seriees tridimensionnelles et IRM

Name:

substriatal gray

Language:

English

Organism:

human

Source:

Crosby-1962

Citation:

New York: MacMillan, 1962

Source Title:

Correlative Anatomy of the Nervous System

Name:

SI

Language:

acronym

Organism:

rat

Source:

Swanson-2004

Citation:

Third Edition, Elsevier Academic Press, Oxford, 2004

Source Title:

Brain Maps: Structure of the Rat Brain.

Species With The Structure
Equivalent By Human Macaque Rat Mouse
Topology Has The Structure Has The Structure Has The Structure Has The Structure

Showing 9 record(s)

Basis:

Topology

Has Equivalent:

Yes

Their Name:

substantia innominata

Basis:

Topology

Has Equivalent:

Yes

Their Name:

Substantia innominata of Meynert

Basis:

Topology

Has Equivalent:

Yes

Their Name:

Substantia innominata of Reichert

Source:

Crosby-1962

Basis:

Topology

Has Equivalent:

Yes

Their Name:

Substantia innominata of Reil

Basis:

Topology

Has Equivalent:

Yes

Their Name:

substriatal gray

Source:

Crosby-1962

Basis:

Topology

Has Equivalent:

Yes

Their Name:

Substantia innominata

Source:

Shantha-1968

Basis:

Topology

Has Equivalent:

Yes

Organism:

Rattus (rat)

Their Name:

substantia innominata

Source:

Bowden-1997

Basis:

Topology

Has Equivalent:

Yes

Organism:

Rattus (rat)

Their Name:

substantia innominata (Reil, Reichert)

Source:

Swanson-1998

Basis:

Topology

Has Equivalent:

Yes

Organism:

Mus (mouse)

Their Name:

substantia innominata

Source:

Hof-2000

Source Page:

45

Models Where It Appears
Structural CNS Model - Macaque

Brain structures of the macaque are illustrated in BrainInfo’s NeuroMaps macaque brain atlas. Structures are grouped by proximity in a hierarchy corresponding to the central nervous system hierarchy of NeuroNames ( Bowden-1995 Martin-2000 ). Structures in the NeuroMaps atlas are based on the segmentation of an MRI of the brain of a 3-year old male rhesus macaque (Macaca mulatta). The atlas is most useful for targeting structures for implantating electrodes and chemtrodes. Updated 29 Oct 2025.

Functional CNS Model - Rat

The Functional CNS Model - Rat (FMrat) ( Swanson-2004) is one of three hierarchical models representing the internal organization of the central nervous system (CNS). The others are the Structural CNS Model - Human (SThmn) and the Functional CNS Model - Human (FMhmn). The FMrat model represents the basic organization of the mouse ( Hof-2000 AMBA-2024 ) and, presumably, other rodents. Functional CNS models differ from structural models in that structures are defined and named by connectivity rather than by proximity to other structures at the same level. Functional models are more useful for representing longitudinal components of are grouped based on information drawn from multiple neuroscientific disciplines. such as connections, neurochemical characteristics, and role in physiogical and behavioral processes. While the Functional Model was developed primarily for an atlas of the rat brain ( Swanson-2004 ), the hierarchical organization of structures is for the most part applicable to the human, macaque, mouse and other mammalian brains as well. Structures at lower levels of the Functional CNS hierarchy are largely the same as in the Classical and Developmental Models, i.e., they were originally identified by stains for gray matter (Nissl substance) and white matter (myelin). At the next higher level they are grouped into basic connectional and functional systems of the CNS, such as the subcortical sensory systems, the brainstem motor system and the behavioral state system. At the highest levels CNS structures are grouped on the basis of dissection and embryologic precursors into cerebrum ( cerebral cortex and cerebral nuclei ), cerebellum, and cerebrospinal trunk.