organum vasculosum (OV)

The term organum vasculosum refers to one of seven predominantly cellular structures of the anterior hypothalamic region as defined by Nissl stain. Located within the lamina terminalis in the optic recess at the anteroventral end of the third ventricle, it is bounded dorsally by the median preoptic nucleus and laterally by the anteroventral periventricular nucleus. Its neuronal composition is similar to that of those adjacent structures. As one of the circumventricular organs, the organum vasculosum is highly vascular and lacks a blood brain barrier ( Saper-2004 ). It is considered the primary detector of dehydration in the control system of drinking ( Graebner-2015 ). It, together with the subfornical organ and the area postrema, constitute the humerosensory system ( Swanson-2004 ).

Also known as: prechiasmatic gland, supraoptic crest, Organum vasculosum of lamina terminalis, vascular organ of lamina terminalis, vascular organ of the lamina terminalis, organum vasculosum

NeuroNames ID: 383

All Names & Sources

Showing 17 synonym(s)

Language
Name
Source
English
organum vasculosum
English
prechiasmatic gland
English
supraoptic crest
English
supraoptic crest
English
vascular organ of lamina terminalis
English
vascular organ of the lamina terminalis
Species With The Structure
Equivalent By Human Macaque Rat Mouse
Topology Has The Structure Has The Structure Has The Structure Relevant Data Not Located

Showing 7 record(s)

Basis
Has Equivalent
Organism
Their Name
Source
Topology
Yes
organum vasculosum
Topology
Yes
Organum vasculosum of lamina terminalis
Topology
Yes
prechiasmatic gland
Topology
Yes
supraoptic crest
Topology
Yes
vascular organ of the lamina terminalis
Topology
Yes
vascular organ of lamina terminalis
Models Where It Appears
Structural CNS Model - Macaque
Functional CNS Model - Rat

The Functional CNS Model - Rat (FMrat) ( Swanson-2004) is one of three hierarchical models representing the internal organization of the central nervous system (CNS). The others are the Structural CNS Model - Human (SThmn) and the Functional CNS Model - Human (FMhmn). The FMrat model represents the basic organization of the mouse ( Hof-2000 AMBA-2024 ) and, presumably, other rodents. Functional CNS models differ from structural models in that structures are defined and named by connectivity rather than by proximity to other structures at the same level. Functional models are more useful for representing longitudinal components of are grouped based on information drawn from multiple neuroscientific disciplines. such as connections, neurochemical characteristics, and role in physiogical and behavioral processes. While the Functional Model was developed primarily for an atlas of the rat brain ( Swanson-2004 ), the hierarchical organization of structures is for the most part applicable to the human, macaque, mouse and other mammalian brains as well. Structures at lower levels of the Functional CNS hierarchy are largely the same as in the Classical and Developmental Models, i.e., they were originally identified by stains for gray matter (Nissl substance) and white matter (myelin). At the next higher level they are grouped into basic connectional and functional systems of the CNS, such as the subcortical sensory systems, the brainstem motor system and the behavioral state system. At the highest levels CNS structures are grouped on the basis of dissection and embryologic precursors into cerebrum ( cerebral cortex and cerebral nuclei ), cerebellum, and cerebrospinal trunk.