area 13l
Acronym: 13l
The term area 13l refers to one of four subdivisions of area 13 in the orbital gyri of human and macaque cerebral cortex. Defined on the basis of multiple stains, it is a narrow, largely granular area located rostral to the agranular orbitofrontal cortex. It is bounded medially by area 13m, laterally by area 47m, and rostrally by area 11l. The other subdivisions are area 13a and area 13b. Its boundaries based on multiple fMRI, functional and connectivity criteria are somewhat different in that the medial boundary is with area OFC, the lateral boundary with area 47s caudally and area 47m rostrally. and the medial boundary with area 11l rostrally and area pOFC caudally. It is activated in THEORY OF MIND-RANDOM, LANGUAGE STORY-MATH, AND FACES-SHAPES contrast tasks and is deactivated in MOTOR CUE-AVG contrast tasks. Other authors have referred to a heavily overlapping area as Fo3 ( Glasser-2016 ).
     Defined by multiple stains in the macaque, identifying features are: 1) a dense horizontal bundle of myelinated fibers in the internal granular layer (IV); 2) bands of cells in the external pyramidal layer (III) and the internal pyramidal layer (V) stain darkly for neurofilament protein by SMI-32, and 3) dense bands of fibers and cells in the external pyramidal layer (III) and internal granular layer (IV) stain for parvalbumin. Another feature that distinguishes area 13l from some adjacent areas is the presence of large pyramidal cells deep in the external pyramidal layer (III) ( Carmichael-1994 )..
     As primarily granular prefrontal cortex, it has no equivalent in the rat ( Wallis-2012 ).

Also known as: No other name for this structure has appeared in PubMed.NeuroNames ID : 3487


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