area 13l - BrainInfo

area 13l (13l)

The term area 13l refers to one of four subdivisions of area 13 in the orbital gyri of human and macaque cerebral cortex. Defined on the basis of multiple stains, it is a narrow, largely granular area located rostral to the agranular orbitofrontal cortex. It is bounded medially by area 13m, laterally by area 47m, and rostrally by area 11l. The other subdivisions are area 13a and area 13b. Its boundaries based on multiple fMRI, functional and connectivity criteria are somewhat different in that the medial boundary is with area OFC, the lateral boundary with area 47s caudally and area 47m rostrally. and the medial boundary with area 11l rostrally and area pOFC caudally. It is activated in THEORY OF MIND-RANDOM, LANGUAGE STORY-MATH, AND FACES-SHAPES contrast tasks and is deactivated in MOTOR CUE-AVG contrast tasks. Other authors have referred to a heavily overlapping area as Fo3 ( Glasser-2016 ). Defined by multiple stains in the macaque, identifying features are: 1) a dense horizontal bundle of myelinated fibers in the internal granular layer (IV); 2) bands of cells in the external pyramidal layer (III) and the internal pyramidal layer (V) stain darkly for neurofilament protein by SMI-32, and 3) dense bands of fibers and cells in the external pyramidal layer (III) and internal granular layer (IV) stain for parvalbumin. Another feature that distinguishes area 13l from some adjacent areas is the presence of large pyramidal cells deep in the external pyramidal layer (III) ( Carmichael-1994 ).. As primarily granular prefrontal cortex, it has no equivalent in the rat ( Wallis-2012 ).

Also known as: area 13l

NeuroNames ID: 3487

All Names & Sources

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Showing 5 synonym(s)

Name:

area 13l

Language:

English

Organism:

human

Source:

Ongur-2003

Citation:

J Comp Neurol. 2003 Jun 2;460(3):425-49.

Source Title:

Architectonic subdivision of the human orbital and medial prefrontal cortex

Name:

13l

Language:

acronym

Organism:

human

Source:

Ongur-2003

Citation:

J Comp Neurol. 2003 Jun 2;460(3):425-49.

Source Title:

Architectonic subdivision of the human orbital and medial prefrontal cortex

Name:

area 13l

Language:

English

Organism:

macaque

Source:

Carmichael-1994

Citation:

Source Title:

Architectonic subdivision of the orbital and medial prefrontal cortex in the macaque monkey

Name:

13l

Language:

acronym

Organism:

macaque

Source:

Carmichael-1994

Citation:

Source Title:

Architectonic subdivision of the orbital and medial prefrontal cortex in the macaque monkey

Name:

Fo3

Language:

acronym

Organism:

human

Source:

Glasser-2016

Citation:

Nature. 2016 August 11; 536(7615): 171–178. doi:10.1038/nature18933.

Source Title:

A multimodal parcellation of human cerebral cortex:

Illustrations

Showing 1 illustration(s)

diagrams of medial and
orbital prefrontal cortex in
human and macaque

No specie structures found

No specie structures available for this concept.

Models Where It Appears

orbitomedial prefrontal cortex hierarchy

refers to the organization of substructures of the orbitomedial prefrontal cortex of the human as described in Ongur-2003. The organization is the same in the macaque, except for a few minor differences in internal structure and names based on topology ( Carmichael-1994 ).

orbitomedial prefrontal cortex

orbital frontal cortex

area 13l

agranular orbitofrontal cortex

Topographic Model of Human Cerebral Cortex

The topographic model of human cerebral cortex is a closed partitive hierarchical model of cerebral cortical structure in the human. The cerebral cortex is segmented on the basis of internal structure, connectivity, and/or functions of cortical areas. It is designed to update the comprehensive early twentieth century parcellations of Brodmann and of von Economo and Koskinas and their successors. A work in progress, it integrates the most authoritative, comprehensive, and recent parcellations and nomenclatures from peer-reviewed publications and neuroanatomical texts. For an equivalent model in the rodent, Search BrainInfo for ' Functional CNS Model - Rat '. This segmentation of the human cerebral cortex, based on a combination of internal structure, connectivity, and function, complements the classical segmentation of the cerebral cortex into lobes, lobules, and gyri based on sulcal patterns: For the classical segmentation, see ' cerebral cortex ' and click 'Locus in Brain Hierarchy'.