area 11l - BrainInfo

area 11l (11l)

The term area 11l refers to the more lateral of two components of area 11 in the human and the macaque. The other is area 11m. Defined on the basis of multiple stains in the human, it occupies the lateral two-thirds of the center of the orbital gyri. It is bounded rostrally by area 10p; caudally, from lateral to medial, by area 47m and area 13l; medially by the other component of area 11, area 11m; and laterally by area 47r. Its boundaries based on multiple fMRI, functional and connectivity criteria are somewhat different in that the rostral boundary is with area a10p, the caudal boundary with area 13l, the lateral boundary with area 47m caudally and area a47r rostrally, and the medial boundary with area OFC caudally and area 10pp rostrally ( Glasser-2016 ). It is activated in CUE, MOTOR CUE, and WORKING MEMORY tasks and deactivated in LANGUAGE STORY, LANGUAGE STORY-MATH, THEORY OF MIND-RANDOM, and FACES-SHAPES contrast tasks. Other authors have referred to a heavily overlapping area as Fo3 ( Glasser-2016 ). Also defined by multiple stains in the macaque, it is distinguished from adjacent areas by its granularity and a bilaminate internal pyramidal layer (V) with aggregates of pyramidal cells revealed by Nissl stain and vertical myelinated fiber bundles in the external granular layer (II), the internal granular layer (IV), and the internal pyramidal layer (V) ( Carmichael-1994 ).. As granular prefrontal cortex, it has no equivalent in the rat ( Wallis-2012 ).

Also known as: area 11l

NeuroNames ID: 3499

All Names & Sources

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Showing 5 synonym(s)

Name:

area 11l

Language:

English

Organism:

human

Source:

Ongur-2003

Citation:

J Comp Neurol. 2003 Jun 2;460(3):425-49.

Source Title:

Architectonic subdivision of the human orbital and medial prefrontal cortex

Name:

11l

Language:

acronym

Organism:

human

Source:

Ongur-2003

Citation:

J Comp Neurol. 2003 Jun 2;460(3):425-49.

Source Title:

Architectonic subdivision of the human orbital and medial prefrontal cortex

Name:

area 11l

Language:

English

Organism:

macaque

Source:

Carmichael-1994

Citation:

Source Title:

Architectonic subdivision of the orbital and medial prefrontal cortex in the macaque monkey

Name:

11l

Language:

acronym

Organism:

macaque

Source:

Carmichael-1994

Citation:

Source Title:

Architectonic subdivision of the orbital and medial prefrontal cortex in the macaque monkey

Name:

Fo3

Language:

acronym

Organism:

human

Source:

Glasser-2016

Citation:

Nature. 2016 August 11; 536(7615): 171–178. doi:10.1038/nature18933.

Source Title:

A multimodal parcellation of human cerebral cortex:

Illustrations

Showing 1 illustration(s)

diagrams of medial and
orbital prefrontal cortex in
human and macaque

No specie structures found

No specie structures available for this concept.

Models Where It Appears

orbitomedial prefrontal cortex hierarchy

refers to the organization of substructures of the orbitomedial prefrontal cortex of the human as described in Ongur-2003. The organization is the same in the macaque, except for a few minor differences in internal structure and names based on topology ( Carmichael-1994 ).

orbitomedial prefrontal cortex

orbital frontal cortex

area 11l

agranular orbitofrontal cortex

Topographic Model of Human Cerebral Cortex

The topographic model of human cerebral cortex is a closed partitive hierarchical model of cerebral cortical structure in the human. The cerebral cortex is segmented on the basis of internal structure, connectivity, and/or functions of cortical areas. It is designed to update the comprehensive early twentieth century parcellations of Brodmann and of von Economo and Koskinas and their successors. A work in progress, it integrates the most authoritative, comprehensive, and recent parcellations and nomenclatures from peer-reviewed publications and neuroanatomical texts. For an equivalent model in the rodent, Search BrainInfo for ' Functional CNS Model - Rat '. This segmentation of the human cerebral cortex, based on a combination of internal structure, connectivity, and function, complements the classical segmentation of the cerebral cortex into lobes, lobules, and gyri based on sulcal patterns: For the classical segmentation, see ' cerebral cortex ' and click 'Locus in Brain Hierarchy'.