entorhinal cortex - BrainInfo

entorhinal cortex (ENT)

The term entorhinal cortex (ENT) refers to a subdivision of the cerebral cortex defined on the basis of internal structure and function in the human ( Mai-1997 ), macaque ( Paxinos-2009a ), rat ( Swanson-2004 ) and mouse (cos) ( Dong-2004 ). In primates it is located in the anterior parahippocampal gyrus (PHGa) of the limbic lobe (LLB), where it is partially bounded ventrolaterally by the collateral sulcus (cos) in the human and by the rhinal sulcus in the macaque (rhs). Rostrally it is superficiall to the amygdala (AMG). It is dorsomedially and caudally adjacent to the hippocampal formation (HPF). Ventrolaterally it is bounded the ectorhinal cortex (ECT). In the rat ( Swanson-2004 ) and mouse ( Franklin-2008 ) it is located ventrally at the occipital pole (ocp) of the cerebral cortex (CTX). . The ENT is subdivided into eight parts in the human ( Insausti-2004 ) and seven parts in the macaque ( Paxinos-2009a ). In the rat and the mouse it is divided into a lateral part of the entorhinal cortex (ENTlt) and a medial part of the entorhinal cortex (ENTme); the latter is further divided into dorsal and ventral zones to produce three subdivisions in the rat ( Swanson-2004 ); The mouse has just two. It's medial part is not divided into zones ( Hof-2000 ). (Updated 10 Dec 2024).

Also known as: Area entorhinalis ventralis et dorsalis, entorhinal area, Area entorhinalis (28,34), Cortex entorhinalis, entorhinal cortex, secondary olfactory cortical area (Carpenter), secondary olfactory cortex, area 28 of Brodmann (Crosby), Area entorhinalis

NeuroNames ID: 168

All Names & Sources

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Showing 22 synonym(s) - Use arrows to navigate

Showing 22 synonym(s)

Name:

ENT

Language:

acronym

Organism:

rat

Source:

Swanson-1998

Citation:

Second Revised Edition, Elsevier Science, Amsterdam, 1998

Source Title:

Brain Maps: Structure of the Rat Brain

Name:

area endorinale (area 28)

Language:

Italian

Organism:

human

Source:

Carpenter-1995

Citation:

EdiSes, s.r.l.- Napoli, 1995

Source Title:

Fondamenti di Neuroanatomia

Name:

entorhinaler Kortex

Language:

German

Organism:

human

Source:

Schiebler-1999

Citation:

Eighth Edition, Springer Verlag, Berlin, 1999.

Source Title:

Anatomie

Name:

area corticale olfattiva secondaria

Language:

Italian

Organism:

human

Source:

Carpenter-1995

Citation:

EdiSes, s.r.l.- Napoli, 1995

Source Title:

Fondamenti di Neuroanatomia

Name:

Area entorhinalis ventralis et dorsalis

Language:

Latin

Organism:

human

Source:

Brodmann-1909

Citation:

IV. Kapitel in Vergleichende Lokalisationslehre der Grosshirnrinde (Leipzig: Verlag von Johann Ambrosias Barth), 1909

Source Title:

Beschreibung der einzelnen Hirnkarten

Name:

area entorrinal

Language:

Spanish

Organism:

human

Source:

Carpenter-1994

Citation:

edicion 4, Williams & Wilkins, Baltimore; traducción de Editorial Medica Panamericana, Buenos Aires, efectuada por el Dr. Alejandro Kaufman

Source Title:

Neuroanatomía Fundamentos

Name:

entorhinal area

Language:

English

Organism:

human

Source:

Carpenter-1983

Citation:

Baltimore: Williams and Wilkins Co., 1983

Source Title:

Human Neuroanatomy

Name:

entorhinal area

Language:

English

Organism:

Macaca fascicularis

Source:

Martin-1997

Citation:

Primate Information Center, University of Washington, Seattle, 1997.

Source Title:

Template Atlas of the Primate Brain

Name:

entorhinal area

Language:

English

Organism:

rat

Source:

Bowden-1997

Citation:

Source Title:

A digital Rosetta stone for primate brain terminology

Name:

Area entorhinalis (28,34)

Language:

Latin

Organism:

human

Source:

Stephan-1975

Citation:

In Handbuch der mikroskopischen Anatomie des Menschen (W. Bargmann, Ed.), Vol. 4, Part 9, 998pp. Springer-Verlag, Berlin and New York.

Source Title:

Allocortex

Name:

Cortex entorhinalis

Language:

Latin

Organism:

human

Source:

Mai-1997

Citation:

San Diego: Academic Press, 1997

Source Title:

Atlas of the Human Brain

Name:

entorhinal cortex

Language:

English

Organism:

human

Source:

Crosby-1962

Citation:

New York: MacMillan, 1962

Source Title:

Correlative Anatomy of the Nervous System

Name:

entorhinal cortex

Language:

English

Organism:

rat

Source:

Bowden-1997

Citation:

Source Title:

A digital Rosetta stone for primate brain terminology

Name:

secondary olfactory cortical area (Carpenter)

Language:

English

Organism:

human

Source:

Carpenter-1983

Citation:

Baltimore: Williams and Wilkins Co., 1983

Source Title:

Human Neuroanatomy

Name:

secondary olfactory cortex

Language:

English

Organism:

human

Source:

Carpenter-1983

Citation:

Baltimore: Williams and Wilkins Co., 1983

Source Title:

Human Neuroanatomy

Name:

area 28 of Brodmann (Crosby)

Language:

English

Organism:

human

Source:

Crosby-1962

Citation:

New York: MacMillan, 1962

Source Title:

Correlative Anatomy of the Nervous System

Name:

Ent

Language:

acronym

Organism:

human

Source:

Mai-1997

Citation:

San Diego: Academic Press, 1997

Source Title:

Atlas of the Human Brain

Name:

Language:

acronym

Organism:

human

Source:

Crosby-1962

Citation:

New York: MacMillan, 1962

Source Title:

Correlative Anatomy of the Nervous System

Name:

Area entorhinalis

Language:

Latin

Organism:

guenon

Source:

Brodmann-1909

Citation:

IV. Kapitel in Vergleichende Lokalisationslehre der Grosshirnrinde (Leipzig: Verlag von Johann Ambrosias Barth), 1909

Source Title:

Beschreibung der einzelnen Hirnkarten

Name:

corteccia endorinale

Language:

Italian

Organism:

human

Source:

Carpenter-1995

Citation:

EdiSes, s.r.l.- Napoli, 1995

Source Title:

Fondamenti di Neuroanatomia

Name:

aire entorhinale

Language:

French

Organism:

human

Source:

Duvernoy-1992

Citation:

Springer-Verlag, Paris, 1992

Source Title:

Le cerveau humain: Surface, coupes seriees tridimensionnelles et IRM

Name:

Language:

acronym

Organism:

human

Source:

Stephan-1975

Citation:

In Handbuch der mikroskopischen Anatomie des Menschen (W. Bargmann, Ed.), Vol. 4, Part 9, 998pp. Springer-Verlag, Berlin and New York.

Source Title:

Allocortex

Illustrations

Showing 3 illustration(s)

labeled line drawings of
sagittal section in
Macaca fascicularis

multiple views of
3D reconstruction in
Macaca mulatta

drawing of
all aspects in
macaque

Species With The Structure

Equivalent By	Human	Macaque	Rat	Mouse
Multiple Criteria	Has The Structure	Has The Structure	Has The Structure	Relevant Data Not Located

1 of 8

Showing 8 record(s) - Use arrows to navigate

Showing 8 record(s)

Basis:

Multiple Criteria

Has Equivalent:

Yes

Organism:

Homo sapiens (human)

Their Name:

area 28 of Brodmann (Crosby)

Source:

Crosby-1962

Basis:

Multiple Criteria

Has Equivalent:

Yes

Organism:

Homo sapiens (human)

Their Name:

Area entorhinalis ventralis et dorsalis

Source:

Brodmann-1909

Basis:

Multiple Criteria

Has Equivalent:

Yes

Organism:

Homo sapiens (human)

Their Name:

entorhinal area

Source:

Carpenter-1983

Basis:

Multiple Criteria

Has Equivalent:

Yes

Organism:

Homo sapiens (human)

Their Name:

entorhinal cortex

Source:

Crosby-1962

Basis:

Multiple Criteria

Has Equivalent:

Yes

Organism:

Homo sapiens (human)

Their Name:

secondary olfactory cortex

Source:

Carpenter-1983

Basis:

Multiple Criteria

Has Equivalent:

Yes

Organism:

Macaca fascicularis (Macaca fascicularis)

Their Name:

entorhinal area

Source:

Martin-1997

Basis:

Multiple Criteria

Has Equivalent:

Yes

Organism:

Rattus (rat)

Their Name:

entorhinal area

Source:

Swanson-2004

Basis:

Multiple Criteria

Has Equivalent:

Yes

Organism:

Rattus (rat)

Their Name:

entorhinal cortex

Source:

Swanson-2004

Models Where It Appears

Structural CNS Model - Macaque

Brain structures of the macaque are illustrated in BrainInfo’s NeuroMaps macaque brain atlas. Structures are grouped by proximity in a hierarchy corresponding to the central nervous system hierarchy of NeuroNames ( Bowden-1995 Martin-2000 ). Structures in the NeuroMaps atlas are based on the segmentation of an MRI of the brain of a 3-year old male rhesus macaque (Macaca mulatta). The atlas is most useful for targeting structures for implantating electrodes and chemtrodes. Updated 29 Oct 2025.

brain

forebrain

endbrain

cerebral white matter

substantia innominata

basal nucleus (basal forebrain nucleus)

islands of Calleja

nucleus accumbens

anterior olfactory nucleus

olfactory tubercle

main olfactory bulb (olfactory bulb)

olfactory peduncle (olfactory tract)

telodiencephalic fissure

midbrain

hindbrain

choroidal fissure

Functional CNS Model - Rat

The Functional CNS Model - Rat (FMrat) ( Swanson-2004) is one of three hierarchical models representing the internal organization of the central nervous system (CNS). The others are the Structural CNS Model - Human (SThmn) and the Functional CNS Model - Human (FMhmn). The FMrat model represents the basic organization of the mouse ( Hof-2000 AMBA-2024 ) and, presumably, other rodents. Functional CNS models differ from structural models in that structures are defined and named by connectivity rather than by proximity to other structures at the same level. Functional models are more useful for representing longitudinal components of are grouped based on information drawn from multiple neuroscientific disciplines. such as connections, neurochemical characteristics, and role in physiogical and behavioral processes. While the Functional Model was developed primarily for an atlas of the rat brain ( Swanson-2004 ), the hierarchical organization of structures is for the most part applicable to the human, macaque, mouse and other mammalian brains as well. Structures at lower levels of the Functional CNS hierarchy are largely the same as in the Classical and Developmental Models, i.e., they were originally identified by stains for gray matter (Nissl substance) and white matter (myelin). At the next higher level they are grouped into basic connectional and functional systems of the CNS, such as the subcortical sensory systems, the brainstem motor system and the behavioral state system. At the highest levels CNS structures are grouped on the basis of dissection and embryologic precursors into cerebrum ( cerebral cortex and cerebral nuclei ), cerebellum, and cerebrospinal trunk.

gray matter (central nervous system gray matter)

white matter (basic fiber systems)

cerebral ventricles (ventricular system)