entorhinal cortex (ENT)

The term entorhinal cortex (ENT) refers to a subdivision of the cerebral cortex defined on the basis of internal structure and function in the human ( Mai-1997 ), macaque ( Paxinos-2009a ), rat ( Swanson-2004 ) and mouse ( Dong-2004 ). In primates it is located in the anterior parahippocampal gyrus (PHGa) of the limbic lobe (LLB), where it is partially bounded ventrolaterally by the collateral sulcus (cos) in the human and by the rhinal sulcus in the macaque (rhs). Rostrally it is superficiall to the amygdala (AMG). It is dorsomedially and caudally adjacent to the hippocampal formation (HPF). Ventrolaterally it is bounded the ectorhinal cortex (ECT). In the rat ( Swanson-2004 ) and mouse ( Franklin-2008 ) it is located ventrally at the occipital pole (ocp) of the cerebral cortex (CTX). . The ENT is subdivided into eight parts in the human ( Insausti-2004 ) and seven parts in the macaque ( Paxinos-2009a ). In the rat and the mouse it is divided into a lateral part of the entorhinal cortex (ENTlt) and a medial part of the entorhinal cortex (ENTme); the latter is further divided into dorsal and ventral zones to produce three subdivisions in the rat ( Swanson-2004 ); The mouse has just two. It's medial part is not divided into zones ( Hof-2000 ). Given the lack of apparent corresponse between the subdivisions of ENT in different species, the names of subdivisions are listed in NeuroNames as synonyms of the parent structure, ENT. Updated 17 Jul 2026.

Also known as: Area entorhinalis ventralis et dorsalis, entorhinal area, Area entorhinalis (28,34), Cortex entorhinalis, entorhinal cortex, secondary olfactory cortical area (Carpenter), secondary olfactory cortex, area 28 of Brodmann (Crosby), Area entorhinalis

NeuroNames ID: 168

All Names & Sources

Showing 22 synonym(s)

Language
Name
Source
English
area 28 of Brodmann (Crosby)
English
entorhinal area
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entorhinal area
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entorhinal area
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entorhinal cortex
English
entorhinal cortex
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secondary olfactory cortex
English
secondary olfactory cortical area (Carpenter)
Species With The Structure
Equivalent By Human Macaque Rat Mouse
Multiple Criteria Has The Structure Has The Structure Has The Structure Relevant Data Not Located

Showing 8 record(s)

Basis
Has Equivalent
Organism
Their Name
Source
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area 28 of Brodmann (Crosby)
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Yes
Area entorhinalis ventralis et dorsalis
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Yes
entorhinal area
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Yes
entorhinal cortex
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Yes
secondary olfactory cortex
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Yes
entorhinal area
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Yes
entorhinal area
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Yes
entorhinal cortex
Models Where It Appears
Structural CNS Model - Macaque

Brain structures of the macaque are illustrated in BrainInfo’s NeuroMaps macaque brain atlas. Structures are grouped by proximity in a hierarchy corresponding to the central nervous system hierarchy of NeuroNames ( Bowden-1995 Martin-2000 ). Structures in the NeuroMaps atlas are based on the segmentation of an MRI of the brain of a 3-year old male rhesus macaque (Macaca mulatta). The atlas is most useful for targeting structures for implantating electrodes and chemtrodes. Updated 29 Oct 2025.

Functional CNS Model - Rat

The Functional CNS Model - Rat (FMrat) ( Swanson-2004) is one of three hierarchical models representing the internal organization of the central nervous system (CNS). The others are the Structural CNS Model - Human (SThmn) and the Functional CNS Model - Human (FMhmn). The FMrat model represents the basic organization of the mouse ( Hof-2000 AMBA-2024 ) and, presumably, other rodents. Functional CNS models differ from structural models in that structures are defined and named by connectivity rather than by proximity to other structures at the same level. Functional models are more useful for representing longitudinal components of are grouped based on information drawn from multiple neuroscientific disciplines. such as connections, neurochemical characteristics, and role in physiogical and behavioral processes. While the Functional Model was developed primarily for an atlas of the rat brain ( Swanson-2004 ), the hierarchical organization of structures is for the most part applicable to the human, macaque, mouse and other mammalian brains as well. Structures at lower levels of the Functional CNS hierarchy are largely the same as in the Classical and Developmental Models, i.e., they were originally identified by stains for gray matter (Nissl substance) and white matter (myelin). At the next higher level they are grouped into basic connectional and functional systems of the CNS, such as the subcortical sensory systems, the brainstem motor system and the behavioral state system. At the highest levels CNS structures are grouped on the basis of dissection and embryologic precursors into cerebrum ( cerebral cortex and cerebral nuclei ), cerebellum, and cerebrospinal trunk.